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Five of the six drugs were simply permutations of existing drugs and therefore did not sell very heavily. The sixth drug, however, addressed hypertension and was a huge success. Since Tazer had a patent on the hypertension drug, it experienced no competition, and profits from the hypertension drug alone kept Tazer in business.
During the past 12 years, Tazer continued a moderate amount of research and development, but it never stumbled upon a drug as successful as the hypertension drug. One reason is that the company never had the motivation to invest heavily in innovative research and development. The company was riding the profit wave generated by its hypertension drug and did not feel the need to commit significant resources to finding new drug breakthroughs.
Now Tazer is beginning to fear the pressure of competition. The patent for the hypertension drug expires in 5 years, 1 and Tazer knows that once the patent expires, generic drug manufacturing companies will swarm into the market like 1 In general, patents protect inventions for 17 years. In 95, GATT legislation extending the protection given by new pharmaceutical patents to 20 years became effective.
Thus, the patent only protects the drug for 17 years. Historical trends show that generic drugs decreased sales of branded drugs by 75 percent. Tazer is therefore looking to invest significant amounts of money in research and development this year to begin the search for a new breakthrough drug that will offer the company the same success as the hypertension drug.
Tazer believes that if the company begins extensive research and development now, the probability of finding a successful drug shortly after the expiration of the hypertension patent will be high.
As head of research and development at Tazer, you are responsible for choosing potential projects and assigning project directors to lead each of the projects.
After researching the needs of the market, analyzing the shortcomings of current drugs, and interviewing numerous scientists concerning the promising areas of medical research, you have decided that your department will pursue five separate projects, which are listed below: Project Up Project Stable Develop an antidepressant that does not cause serious mood swings.
Develop a drug that addresses manicdepression.
Develop a vaccine to prevent HIV infection. Develop a more effective drug to lower blood pressure. For each of the five projects, you are only able to specify the medical ailment the research should address, since you do not know what compounds will exist and be effective without research. You also have five senior scientists to lead the five projects.
You know that scientists are very temperamental people and will work well only if they are challenged and motivated by the project. To ensure that the senior scientists are assigned to projects they find motivating, you have established a bidding system for the projects. You have given each of the five scientists bid points. They assign bids to each project, giving a higher number of bid points to projects they most prefer to lead.
The following table provides the bids from the five individual senior scientists for the five individual projects: Project Dr. Kvaal Dr. Zuner Dr. Tsai Dr. Mickey Dr.
What are the assignments? Rollins is being courted by Harvard Medical School to accept a teaching position. You are fighting desperately to keep her at Tazer, but the prestige of Harvard may lure her away. If this were to happen, the company would give up the project with the least enthusiasm.
Which project would not be done? You decide that either Dr. Zuner or Dr. Mickey could lead two projects. Under these new conditions with just four senior scientists, which scientists will lead which projects to maximize preferences? Zuner was informed that she and Dr. Mickey are being considered for two projects, she decided to change her bids.
The following table shows Dr. Zuner s new bids for each of the projects: Project Up 20 Project Stable Project Choice Project Hope 39 Project Release 40 Under these new conditions with just four scientists, which scientists will lead which projects to maximize preferences? Why or why not? You decide, however, that several scientists cannot lead certain projects.
In particular, Dr. Mickey does not have experience with research on the immune system, so he cannot lead Project Hope. His family also has a history of manic-depression, and you feel that he would be too personally involved in Project Stable to serve as an effective project leader.
Mickey therefore cannot lead Project Stable. Kvaal also does not have experience with research on the immune systems and cannot lead Project Hope.
In addition, Dr. Finally, Dr. Rollins cannot lead Project Up because her family has a history of depression and you feel she would be too personally involved in the project to serve as an effective leader.
Mickey and Dr. Kvaal cannot lead two of the five projects, they each have only bid points. Rollins has only bid points because she cannot lead one of the five projects. The following table provides the new bids of Dr.
Mickey, Dr. Kvaal, and Dr. Rollins: Project Dr. Therefore, each of these projects will be assigned two scientists as project leaders. You decide to hire two more scientists in order to staff all projects: Dr. Arriaga and Dr. Because of religious reasons, the two doctors both do not want to lead Project Choice. The following table lists all projects, scientists, and their bids.
He surveys the destruction surrounding him shattered windows, burning buildings, torn roads and smiles. His two years of work training revolutionaries east of the Ural Mountains has proved successful; his troops now occupy seven strategically important cities in the Russian Federation: Kazan, Perm, Yekaterinburg, Ufa, Samara, Saratov, and Orenburg. His siege is not yet over, however. He looks to the west. Given the political and economic confusion in the Russian Federation at this time, he knows that his troops will be able to conquer Saint Petersburg and Moscow shortly.
Commander Votachev will then be able to rule with the wisdom and control exhibited by his communist predecessors Lenin and Stalin. Across the Pacific Ocean, a meeting of the top security and foreign policy advisers of the United States is in progress at the White House.
The President has recently been briefed about the communist revolution masterminded by Commander Votachev and is determining a plan of action. The President reflects upon a similar October long ago in 17, and he fears the possibility of a new age of radical Communist rule accompanied by chaos, bloodshed, escalating tensions, and possibly nuclear war. He therefore decides that the United States needs to respond and to respond quickly. Moscow has requested assistance from the United States military, and the President plans to send troops and supplies immediately.
The President turns to General Lankletter and asks him to describe the preparations being taken in the United States to send the necessary troops and supplies to the Russian Federation. General Lankletter informs the President that along with troops, weapons, ammunition, fuel, and supplies, aircraft, ships, and vehicles are being assembled at two port cities with airfields: Boston and Jacksonville.
The aircraft and ships will transfer all troops and cargo across the Atlantic Ocean to the Eurasian continent.
The general hands the President a list of the types of aircraft, ships, and vehicles being assembled along with a description of each type. The list is shown below. Transportation Type Name Capacity Speed Aircraft C Starlifter 0 tons miles per hour Ship Transport tons 35 miles per hour Vehicle Palletized Load 16, kilograms 60 miles per hour System Truck All aircraft, ships, and vehicles are able to carry both troops and cargo. Once an aircraft or ship arrives in Europe, it stays there to support the armed forces.
The President then turns to Tabitha Neal, who has been negotiating with the NATO countries for the last several hours to use their ports and airfields as stops to refuel and resupply before heading to the Russian Federation.
She informs the President that the following ports and airfields in the NATO countries will be made available to the United States military.
Ports Napoli Hamburg Rotterdam Airfields London Berlin Istanbul The President stands and walks to the map of the world projected on a large screen in the middle of the room. The three cities are Saint Petersburg, Moscow, and Rostov. He explains that the troops and cargo will be used both to defend the Russian cities and to launch a counterattack against Votachev to recapture the cities he currently occupies.
The map is shown at the end of the case. The President also explains that all Starlifters and transports leave Boston or Jacksonville. Esercizi per il corso di ricerca operativa 1 ; Esercizi per il corso di ricerca operativa 1 Ultimo aggiornamento: 8 gennaio Read esercizi di ricerca operativa online, read in mobile or Kindle.
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